The LAR failing to exceed 15% on day 1 (second day from the ICU admission) was used to predict the high risk for sepsis in trauma patients (Rozanovic et al., 2016), whereas the serum MCP-1 levels >240.7 pg/ml on day 0 (within 24 h of admission) was used for the same purpose of identifying patients with trauma at high risk for sepsis development (Wang et al., 2018). This evidence concerns the gene CCL2 and Sepsis.