In human colon cancers (based on The Cancer Genome Atlas (TCGA) data), the expression of endogenous PP2A inhibitors, CIP2A and SET, correlated positively with the infiltration of CD8+ T cells and CD20+ B cells and negatively with FOXP3+ Treg cells (Fig. 1c). This evidence concerns the gene CIP2A and malignant colon neoplasm.