To identify the binding partners of Ppp2r1a for this function, we performed immunoprecipitation followed by mass spectrometry (IP/MS) in normal intestinal organoid cultures and analysed the enriched pathways by comparing transcriptomes between normal and Ppp2r1a−/− intestinal tumour organoid cultures (Fig. 3a). The gene discussed is PPP2R1A; the disease is neoplasm.