IP/MS identified several known proteins, such as protein phosphatase 2 catalytic subunit beta (PPP2CB), retinoblastoma protein (Rb)23 and AKT124 in ovarian carcinoma and HEK cells and unknown proteins, such as histone deacetylase (HDAC)2, interacted with and regulated by Ppp2r1a (Supplementary Data 1). This evidence concerns the gene PPP2CB and ovarian carcinoma.