Analysis of human CRC TCGA data (Fig. 2i) and immunohistochemical profiling by tissue array (Fig. 2j and Supplementary Table 7) also revealed that MSI increased both the mRNA and protein levels of CIP2A and SET but decreased the PPP2R1A level compared to those of MSS (Fig. 2i). This evidence concerns the gene CIP2A and colorectal carcinoma.