SERPINA3 and schizophrenia: Regardless of reduced microglia marker expression, the prefrontal cortex of people with schizophrenia has increased expression of the pro-inflammatory cytokines interleukin (IL) 6 (IL6), IL1B and CXC motif chemokine ligand 8 (CXCL8, also IL8), and a general inflammation marker serpin family A member 3 (SERPINA3), which is induced in response to pro-inflammatory cytokines [23, 24].