IL1R1 mRNA was significantly different across diagnostic groups [Supplementary Fig. S1, ANCOVA (RIN), F(2,84) = 4.28, p = 0.017], with increased expression in schizophrenia (62%, p = 0.004) but not in bipolar disorder compared to controls (p = 0.14). This evidence concerns the gene IL1R1 and schizophrenia.