Block et al5, in a post hoc analysis assessing a large cohort ofpatients undergoing dialysis, suggested that biochemical markers involved in CKD-MBDhave limited prognostic implication, since several CKD-MBD phenotypic behaviors areobserved, according to KDIGO1/KDOQI6 targets, when based on calcium, phosphorus and PTH. This evidence concerns the gene PTH and chronic kidney disease.