SLC34A3 and nephrocalcinosis: The presence of nephrocalcinosis or nephrolithiasis in a patient prior to initiation of therapy, suggests diseases associated with hypercalciuria such as HHRH (NaPi 2C defects), Dent disease 1(CLCN5 defect) or hypophosphatemia and nephrocalcinosis (NaPi2a defects).