Genetic defects of NaPi2A and NaPi2C result in renal phosphate wasting, causing hypophosphatemia and nephrocalcinosis, also known as idiopathic infantile hypercalcemia (IIH) and hypophosphatemic rickets with hypercalciuria (HHRH), respectively [13–15]. This evidence concerns the gene SLC34A3 and nephrocalcinosis.