These eight targets with higher values of ‘Degree’ (above twofold of the median value) were identified as the candidate semen armeniacae amarum targets for COVID-19, including IL6(51), SRC(50), MAPK3(50), MAPK1(50), EGFR(46), VEGFA(46), HRAS(45) and CASP3(43). The gene discussed is MAPK3; the disease is COVID-19.