A recent study summarised that gain‐of‐function mutations in STIM1 and ORAI1 genes were associated with TAM and Stormorken syndrome (TAM/STRMK), in contrast, loss‐of‐function mutations were associated with CRAC channelopathy involving immunodeficiency and autoimmunity, muscle hypotonia, ectodermal dysplasia and mydriasis.31 Here, ORAI1 is linked to Autoimmunity.