EGFR and head and neck squamous cell carcinoma: Unlike in NSCLC, where activating mutation, high EGFR expression (Pearson’s R = − 0.3675, P = 0.0120) and dependency (Pearson’s R = 0.4757, P = 0.105) were associated with osimertinib sensitivity, EGFR expression (Pearson’s R = 0.2957, P = − 0.1341) and dependency (Pearsons’ R = 0.2723, P = 0.1980) were not associated with osimertinib sensitivity in HNSCC [Fig. S4B–C].