From the RT-qPCR results in the aforementioned 63 pairs of tissues, we observed that the expression of miRNA-130a-3p in HCC tissue was dramatically reduced compared to the paired adjacent tissues, and the expression of miRNA-130a-3p was positively associated with HCC prognosis (Fig. 3C–E), which demonstrated a negative correlation between LINC00667 and miRNA-130a-3p (Fig. 3F). This evidence concerns the gene LINC00667 and hepatocellular carcinoma.