In addition to Myc and Bcl2 (Fig. 2i), other tumor-promoting genes such as Eef2 and Myh10 were upregulated in leukemia cells, whereas tumor suppressors such as Ikzf1, Ikzf2, Arid1b, Arid2, Samhd1, Bach2, and Myo18b were downregulated (Fig. 6d and Supplementary Data 4). This evidence concerns the gene SAMHD1 and leukemia.