The following five AD genes showed good evidence of mosaicism in gnomAD, as found using ExAC: ASXL1, BRAF, CBL, DNMT3A and IDH2 (Table 2; with only DNMT3A and IDH2 alleles being flagged for failing of the gnomAD random forest filter). The gene discussed is DNMT3A; the disease is Alzheimer disease.