The histone methyltransferase G9a (EHMT2) and the PAX3-FOXO1 fusion oncogene are regulated by NR4A1 in ARMS cells [21, 25] and treatment of Rh30 cells with 25 and 50 μM kaempferol and quercetin decreased expression of G9a and PAX3-FOX01 gene products (Fig. 4A). Here, PAX3 is linked to alveolar rhabdomyosarcoma.