IHC staining showed that the tumor cells exhibited a strong and diffuse nuclear expression of transducin-like enhancer 1 (TLE1; Fig. 3C, J), a new nuclear marker for synovial sarcoma that is considered helpful in distinguishing synovial sarcoma from its histologic mimics, particularly when nuclear staining is moderate or strong [4]. This evidence concerns the gene TLE1 and synovial sarcoma.