After DnCPV-23 infection, it was speculated that the D. nerii tended to strengthen the elimination of lipophilic endobiotics such as hormones and xenobiotics including phytoalexins and drugs conjugated by invertebrates and plants mainly with glucose [42] through promoting the transcription of UGTs by regulating the activities of nuclear-receptor family (CAR, PXR, FXR, LXR, and PPAR), the arylhydrocarbon receptor [43] or ubiquitous transcription factors (FOXA1, Sp1, and Cdx2) [44]. Here, FOXA1 is linked to infection.