IGF1 and adenomyosis: Functional, co-expression, correlation analyses of proliferative phase endometrial tissues from adenomyosis vs. controls found that decreased METTL3 expression in adenomyosis led to declining total m6A levels and the downstream increased insulin-like growth factor-1 (IGF1) and D-Dopachrome Tautomerase (DDT); and it revealed that IGF1 and DDT might correlate with epithelial cell proliferation and migration, both of which are involved in the pathogenesis of adenomyosis [38].