The results of GSEA revealed that the samples of highly expressed ARNTL2 were mainly enriched in “olfactory transduction”, “cytokine-cytokine receptor interaction”, “systemic lupus erythematosus”, “natural killer cell-mediated cytotoxicity” and “cell cycle” (Additional file 1: Fig. S6A), whereas the samples of lowly expressed ARNTL2 were mainly enriched in “GNRH signaling pathway”, “Arachidonic acid metabolism”, and “alpha linolenic acid metabolism” (Additional file 1: Fig. S6B). The gene discussed is BMAL2; the disease is systemic lupus erythematosus.