TIMP2 and acute kidney injury: Combining renal cell arrest biomarker (u[TIMP-2]*[IGFBP7]) with renal damage biomarkers (uKIM-1 and uIL-18) improved the performance for predicting AKI progression, with AUCs of 0.752 for u[TIMP-2]*[IGFBP7] with uKIM-1, and 0.747 for u[TIMP-2]*[IGFBP7] with uIL-18, respectively (Table 3).