For predicting AKI progression with death, u[TIMP-2]*[IGFBP7] also showed the greatest AUC (0.777, 95%CI 0.700-0.854) as compared to uKIM-1 (AUC 0.738, 95%CI 0.653-0.822), and uIL-18 (AUC 0.657, 95%CI 0.557-0.758) (Supplemental Table S1). This evidence concerns the gene IGFBP7 and acute kidney injury.