It was found in another study that METTL14, as the upstream target of miR‐375, suppresses CRC cells propagation via the miR‐375—Yes‐associated protein 1 (YAP1) axis, and depresses migration and aggression of CRC cells via the miR‐375 ‐ SP1 axis.57 This evidence concerns the gene SP1 and colorectal carcinoma.