AKT1 and renal cell carcinoma: Studies have found that the VHL‐HIF‐ZNF217‐METTL14‐mediated hypoxia pathway affects generation and sustentation of the RCC cancer stem cells by regulating m6A levels, and mediates oncogenesis and development of ccRCC via the PI3K/AKT/mTOR and p53 signaling pathways that are the downstream targets of m6A.67