ICAM1 and eosinophilic esophagitis: In keeping with this, we showed that fibroblasts tether eosinophils in vitro, that high eosinophilia correlates positively with the abundance of ICAM-1+ fibroblasts extracted from active EoE patients and cultured in vitro, and that blockade of ICAM-1 leads to reduced eosinophil adhesion in co-culture with fibroblasts17.