To identify the expression status of circFOXM1 in HCC cells, circFOXM1 expression levels in different HCC cells (Huh7, HepG2, Hep3B, HCCLM3 and MHCC97-H) and the normal human hepatocytes (MIHA) were compared, which showed that circFOXM1 expressions in Huh7, HepG2, Hep3B, HCCLM3 and MHCC97-H cells were all significantly upregulated versus MIHA, with the highest expression level in Huh7 cells (Fig. 1A). The gene discussed is XIAP; the disease is hepatocellular carcinoma.