Antibodies against mGluR2 efficiently blocked the infection of rVSV-SARS-CoV-S and rVSV-MERS-CoV-S in Vero-E6 cells (Supplementary Fig. S6f), but failed to block the infection of VSV in Vero-E6 cells (Supplementary Fig. S6e). Here, GRM2 is linked to infection.