Moreover, miR-411-5p expression was notably downregulated in HCC tissues compared to adjacent non-tumor tissues (P < 0.0001, Supplementary Fig. 6C) and negatively correlated with KDM4A-AS1 expression in HCC tissues (P = 0.0006, r = −0.3533, Supplementary Fig. 6D). Here, KDM4A is linked to neoplasm.