BMPR2 and osteosarcoma: The luciferase reporter assay results (Table 7) showed that compared with BMPR2-wt+mimic-NC group, the amount of luciferase expression in osteosarcoma cells was significantly reduced in BMPR2-wt+mimic-miR-200a group (P < 0.05), whereas the amount of luciferase expression in osteosarcoma cells in BMPR2-mut+mimic-miR-200a was not significantly different from that in BMPR2-mut+mimic-NC group.