SH2D3A and infection: While the rD6/2-2g-NSP1-null RV stock used for inoculation carried the mutations (Fig. S3A), NSP1 fragments amplified from the feces of the rD6/2-2g-NSP1-null-infected mice were indistinguishable from those from rD6/2-2g infection (Fig. S3B), indicating that RV in the fecal specimens readily reverted to the wild-type sequences.