Based upon the comparison with a group of 224 glioblastoma patients defined per histopathology according to the WHO 2016 classification, we aim to describe pattern and extend of MGMT promotor methylation in IDHwt astrocytoma with pTERTmut and its association with survival in the presence of chemo- and radiotherapy. Here, MGMT is linked to astrocytoma (excluding glioblastoma).