The critical role of AVP in controlling water/salt balance is well established.55,56 AVP is also known to escalate inflammation, which further contributes to neuronal disruptions after traumatic brain injury,57 in addition to its association with SCI-induced polyuria.9,10 Whereas SON analysis revealed a significant decrease in AVP-labeled cells at 14 dpi, there were no other time points that demonstrated significant differences compared to surgical sham animals. The gene discussed is AVP; the disease is Polyuria.