These receptors also play major roles in salt and fluid balance within the body, as well as cardiovascular homeostasis.12,13 Clinically, desmopressin (synthetic AVP) may be used to treat nocturnal polyuria, but with limited results and potential deleterious side effects.14,15 Additionally, desmopressin often impacts blood pressure, which may increase bouts of autonomic dysreflexia—a phenomenon that occurs when blood pressure rises uncontrollably and cannot be corrected because of disruptions of descending sympathetic pathways in the spinal cord.16,17. Here, AVP is linked to Polyuria.