PPARG and Alzheimer disease: Because telmisartan is also a peroxisome proliferator-activated receptor (PPAR)-γ agonist capable of exerting anti-inflammatory effects in neurons, these results indicate it may be a particularly useful ARB for the treatment of AD through its combined PPAR-γ and AT1R blockades, resulting in attenuated Aβ deposition (Mogi et al., 2008) and improved cognitive outcomes (Tsukuda et al., 2009).