There were significant differences in the relative expression of ANRIL between CHD patients with different ages, history of smoking, history of hypertension, high total cholesterol (TC), high triglyceride (TG), and high homocysteine (Hcy) (P < 0.05), not between those with different genders, types of CHD, history of drinking, and history of diabetes (P > 0.05). The gene discussed is CDKN2B-AS1; the disease is diabetes mellitus.