Univariate Cox regression analysis showed that age, BMI, NYHA class, diabetes mellitus, atrial fibrillation, smoking, eGFR, lg NT-proBNP, hemoglobin, albumin, LDL-C, and LEV were associated with MACEs (unadjusted hazard ratio 1.305, 95% CI 1.152–1.485, P < 0.0001). Here, NPPB is linked to atrial fibrillation.