Due to the limitation in using a single lipid index to evaluate the relationship between dyslipidemia and CVD events and all-cause mortality, some studies proposed that apolipoprotein B (ApoB), apolipoprotein AI (ApoAI), lipoprotein (a) [Lp(a)] or lipid ratios had an additional clinical value, and recommended to attach importance to the measurement of ApoB in clinical practice (11–14). This evidence concerns the gene APOB and metabolic syndrome.