In model 2 excluding etiology, we found that male gender (OR = 2.884, 95% CI: 1.360–6.115, p = 0.006), BMI (OR = 0.879, 95% CI: 0.812–0.951, p = 0.001), albumin (OR = 0.934, 95% CI: 0.882–0.989, p = 0.019), and visceral adiposity (OR = 3.413, 95% CI: 1.344–8.670, p = 0.010) were independent risk factors of malnutrition risk determined by RFH-NPT in hospitalized patients with cirrhosis. This evidence concerns the gene ALB and Cirrhosis.