CASP3 and neoplasm: ↑ The cellular uptake of DOX-loaded nanomicelles, micelles' permeability, the transport ratio of DOX BO-PMs, anti-proliferation efficacy, the caspase-3 activity, TUNEL-positive cell ↓ IC50, C6 cell migration, the time to peak in brain, tumor volume, hemorrhaging and necrosis cell