↑ RIPK1, FADD mRNA and protein level; pharmacokinetic parameters (t1/2β, AUC0−24h, MRT); survival rate; NB concentration in the tumor region ↓ EHD1 mRNA and protein level; CI; tumor volume index, tumor volume, tumor weight; PCNA, Ki67. The gene discussed is RIPK1; the disease is neoplasm.