Of these genes, 14 DEGs were found to be markedly related to OS of TCGA-derived PCa cases (p < 0.01) through Cox proportional hazards analysis, which included 2 low-risk DEGs (GAD1 and CT83; HR < 1) and 12 high-risk ones (SLC17A9, KIAA1549L, AC079949.2, LYPD8, SNX25P1, IGKV1D-12, TRIM50, OLFML2B, SEMG1, RNU6-126P, INAFM2, and MIR4728; HR > 1) (Figure 1K). Here, LYPD8 is linked to posterior cortical atrophy.