TNFRSF1B and breast neoplasm: After the treatment with increasing dose of anti-TNFR2 antibody (1, 5, 10, 25, and 50 μg/ml), CCK-8 cell proliferation assay showed that anti-TNFR2 antibody could inhibit the proliferation of mouse breast tumor cell line 4T1 in a dose-dependent manner (Figure 2A).