The clinical identification and diagnosis of neonatal sepsis is confirmed by blood culture (27, 28), and the assessment of acute phase reactants includes C-reactive protein (CRP) (29, 30), procalcitonin (30, 31), presepsin (32, 33), and inflammatory mediators such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNFα) (34, 35). This evidence concerns the gene TNF and Neonatal sepsis.