Our interest in FoxP3 is also related to its ability to associate with the polycomb proteins EZH2/PRC2 complex and play a role in epigenetic regulation (63–67) and modulating the expression of tumor associated genes The polycomb group of proteins (PRC1 and PRC2) plays important roles in cell growth and proliferation (68, 69). The gene discussed is EZH2; the disease is neoplasm.