Through these studies presented here, we provided evidence that endometriotic PF increases proliferation, induces inflammatory genes (including FoxP3 mediated signaling) and modulates EZH2/H3K27me3 in human clear-cell ovarian carcinoma cell lines (TOV-21G) compared to normal ovarian epithelial cells (IOSE). This evidence concerns the gene FOXP3 and ovarian clear cell cancer.