TNF and stage 5 chronic kidney disease: (38) have demonstrated that the A allele positivity in 308 gene loci confers approximately to a 3.0-fold increased susceptibility to malnutrition and cachexia in patients with end-stage renal disease (38), to consolidate the present data regarding TNF-α 308G/A gene polymorphism in both the pancreatic and NSCL cancer patients.