Particularly of interest is galectin-3 binding protein, which we found to be upregulated in different grades of glioma and has also been reported in The Human Protein Atlas v15 (www.proteinatlas.org) to be localized in vesicles of glioblastoma cell lines and overexpressed in glioma tissue (74). The gene discussed is LGALS3BP; the disease is central nervous system cancer.