Analysis by Max Quant identified 34, 21, and 14 proteins to be differentially abundant by more than 1.3-fold in the three grades of glioma, respectively, in comparison with the control samples, out of which, seven proteins were found to be differentially abundant in all three grades (Figure 3C), with galectin-3 binding protein, C-reactive protein (CRP), and Serum amyloid A2 (SAA2) being upregulated across all grades. The gene discussed is LGALS3BP; the disease is central nervous system cancer.