Urine is an ideal source of PCa biomarkers because the samples can be collected noninvasively in large amounts, and several urinary markers have been reported such as prostate cancer antigen-3 (PCA3), transmembrane protease serine-2 (TMPRSS2), and glutathione S-transferase P (GSTP1) gene (4–7). Here, TMPRSS2 is linked to posterior cortical atrophy.