PD-L1 IHC 22C3 pharmDx, a PD-L1 antibody reagent, was approved by the NMPA as a qualitative immunohistochemical assay to assess PD-L1 expression in formalin-fixed, paraffin-embedded NSCLC biopsy/surgical pathology specimens using a monoclonal mouse anti-PD-L1 antibody (clone 22C3, code M3653, Dako) on May 8, 2020 (88). Here, CD274 is linked to non-small cell lung carcinoma.