MYCN and skin basal cell carcinoma: Previous studies, including whole-exome sequencing (WES) analyses, have also recognized other genes/pathways frequently mutated in BCC, including TP53, MYCN, PPP6C, PTPN14, STK19, and LATS1 (14, 15), as well as genes involved in the RTK-RAS-PI3K and Hippo-YAP pathways (15).