Of note, high expression of FoxM1 and its downstream effector factors (Plk1, CyclinB1, Skp2 and Aurora B Kinase) correlated with poor overall survival in hepatic cancer patients (Supplementary Figures 1A–E, analyzed from RNA-seq data available on Kaplan-Meier plotter) (53). The gene discussed is SKP2; the disease is liver cancer.