GCS: Glasgow Coma Scale, COPD: Chronic obstructive pulmonary disease, CVE: Cerebrovascular event, CK: Creatine kinase, AST: Aspartate aminotransferase, ALT: Alanine aminotransferase; CRP: c-reactive protein test; SD: Standard deviation. The gene discussed is CRP; the disease is chronic obstructive pulmonary disease.