GCS: Glasgow Coma Scale; COPD: Chronic obstructive pulmonary disease; CVE: Cerebrovascular event; CK: Creatine kinase; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; SpO2: Saturation of peripheral oxygen; CRP: c-reactive protein test; SD: Standard deviation. This evidence concerns the gene CRP and chronic obstructive pulmonary disease.