LGALS3 and androgen insensitivity syndrome: Firstly, it was based on a cross-sectional study of a small sample, and studies from different regions and ethnic groups are still needed to support our conclusions; secondly, we did not do dynamic monitoring of serum galectin-3 levels and MoCA scores; thirdly, we did not collect the infarct location and volume of AIS, and these data may affect the prognosis; finally, we did not further do interventional experiments in animal and cell models.