SUMO1 and atherosclerosis: Considering the three significant modules of the atherosclerosis-GSE23746 dataset, two core crosstalk genes Formin Homology 2 Domain Containing 1 (FHOD1) and RAS Guanyl Releasing Protein 2 (RASGRP2) were identified in the blue module (Figure 11(a)), as well as four core crosstalk genes VAMP7, Sorting Nexin 3 (SNX3), Cell Cycle Progression 1 (CCPG1), and PEST Proteolytic Signal Containing Nuclear Protein (PCNP) were identified in the green module (Figure 11(b)), while two core crosstalk genes (HMGB1 and SUMO1) were identified in the turquoise module.