CHEK2 and posterior cortical atrophy: Further detection results showed that miR-145-5p overexpression could upregulate the expression of ChK2, and overexpression of miR-145-5p could upregulate the expression of p-p38MAPK; this finding suggests that miR-145-5p induced apoptosis of PCa cells by upregulating the expression of the pro-apoptotic protein (Figures 3(a) & 3(b)).