The optimal HCC gene panel included DST, SYNE2, APOB, KDM6A, USP9X, SPAG17, TERT, TP53, AMPH, EP300, TTK, CCND1, FCRL1, IL6ST, PTEN, SFN, STK11, and NRAS. Here, NRAS is linked to hepatocellular carcinoma.