The most commonly mutated genes among patients with CHB, LC, and HCC included DST, ZFHX4, SYNE2, PEG3, ASPM, KEAP1, KDM6A, PTPRB, FRAS1, APOB, MAP1B, RPS6KA3, USP9X, BRD7, SPAG17, ACVR2A, IDH2, AR, TERT, TP53, TGFBR2, EP300, STAT3, and DDR2. This evidence concerns the gene TP53 and laryngotracheoesophageal cleft.