Of the six affected individuals with homozygous truncation in GCOM1, one had pacemaker (PM) and later heart transplantation, four suffered from ventricular and atrial arrhythmias, one had only ventricular arrhythmias, and one had no recorded arrhythmias but suffered SCD (Table 1). This evidence concerns the gene GCOM1 and Schnyder corneal dystrophy.