CD8A and neoplasm: In the TARGET cohort, the patients in the high PRS-score group had lower levels of tumor infiltration by CD8+ T cells, dendritic cells (DCs), macrophages, neutrophils, natural killer cells, plasmacytoid dendritic cells (pDCs), Th2 cells, Tfh cells, and tumor-infiltrating lymphocytes (TILs) compared with the patients in the low PRS-score group (Figure 8E).