CD8A and neoplasm: In the GEO cohort, compared with the patients in the low PRS-score group, the patients in the high PRS-score group had lower levels of tumor infiltration by immune cells, including CD8+ T cells, DCs, macrophages, neutrophils, pDCs, TILs, T regulatory, Tfh, Th1, and Th2 cells (Figure 8G).