NPM1 and neoplasm: The results of RT-PCR showed that the relative expression levels of five hub genes, including WYC, CCND1, WNT5A, HIST1H2BH, and NPM1 were higher in RD-ES cells than in MSCs (Figure 7A), while in the A673 cell line, in addition to MYC, the remaining four hub genes were also significantly overexpressed in the tumor (Figure 7B).